माइक्रोबायोलॉजी और पैथोलॉजी जर्नल

Inflammatory Bowel Disease (IBD), including Crohn's disease and ulcerative colitis, poses significant challenges in management due to its chronic and relapsing nature. Fecal Microbiota Transplantation (FMT) has emerged as a promising therapeutic option, aiming to restore the dysbiotic gut microbiota associated with IBD. This review explores the importance of FMT in managing IBD by examining its mechanisms of action, clinical efficacy, safety profile and future directions. Evidence from preclinical studies, clinical trials and real-world experiences is synthesized to elucidate the role of FMT in inducing remission, reducing disease activity and improving quality of life in IBD patients. Moreover, considerations such as donor selection, delivery methods and long-term outcomes are discussed to optimize the implementation of FMT in clinical practice. Overall, FMT holds immense potential as a safe and effective adjunctive therapy for IBD, offering novel insights into the interplay between the gut microbiota and host immune system.

Burn injuries pose significant challenges to healthcare providers due to their complex nature and potential for severe morbidity and mortality. Accurate assessment of burn size is crucial for guiding treatment decisions and predicting patient outcomes. This paper provides a comprehensive review of the technical and medical considerations involved in the evaluation and recording of burn size. Traditional methods such as the Lund and Browder chart have long been used for burn assessment, but advancements in technology have introduced new tools and techniques, including digital imaging and three-dimensional scanning. This review examines the advantages, limitations and practical applications of various assessment methods, emphasizing the importance of considering factors such as depth and anatomical location. Additionally, common challenges and sources of error in burn size estimation are discussed, highlighting the need for ongoing education and training of healthcare professionals. Overall, a thorough understanding of the technical and medical aspects of burn size assessment is essential for improving patient care and outcomes in burn management.

The microbiological safety of ice is critical in industrial food facilities where it serves various purposes, including food preservation and beverage service. However, conventional methods of ice production often fall short in controlling microbial contamination, posing risks of foodborne illnesses. This paper explores the use of Hydrogen Peroxide (H2O2) as a novel approach to improve the microbiological stability of ice in industrial food settings. Through various concentrations and application methods of hydrogen peroxide, significant reductions in microbial contamination, including bacteria and fungi, were observed in ice samples. Furthermore, sensory evaluations revealed no adverse effects on ice quality or taste perception post-treatment. This study underscores the potential of hydrogen peroxide as an effective and safe method for enhancing the microbiological safety of ice in industrial food facilities, thereby advancing food safety standards and reducing the risk of foodborne pathogens transmission.

The management of bacterial wilt disease in tomato plants poses a significant challenge to global agriculture. Nanoparticles have emerged as promising tools for disease control due to their unique physicochemical properties. This study investigates the impact of nanoparticle exposure on tomato bacterial wilt disease through modulation of the rhizosphere bacterial community. Tomato plants were treated with Silver Nanoparticles (AgNPs), Copper Nanoparticles (CuNPs) and Zinc Oxide Nanoparticles (ZnONPs) and their effects on disease suppression and rhizosphere bacterial composition were assessed. Next-generation sequencing of bacterial DNA revealed significant alterations in the rhizosphere microbiome following nanoparticle exposure. Furthermore, nanoparticle-treated plants exhibited varying degrees of disease suppression compared to control plants. Our findings highlight the potential of nanoparticle-mediated modulation of rhizosphere bacterial communities as a novel strategy for enhancing plant health and combating bacterial wilt disease in tomatoes.