प्रत्यारोपण प्रौद्योगिकी एवं अनुसंधान

Pulmonary Function Assessment Method with Type II Non-heart Beating Donors in Spain is Valid

Abstract

Jose Carlos Meneses

Lung transplantation unit from Hospital 12 de Octubre began its work in October 2008. In the last five years, 80 lung transplants have been performed with a hospital mortality rate of 6.5% and a five years survival of 79.7%. As a result of the need of obtaining a greater number of donors, and encouraged by the outpatient non heart beating donors program within our hospital, we considered the possibility of assessing these donors lung grafts. We have followed the methodology designed and set off with good results by other hospitals in the area of Madrid. Nevertheless some changes have been included such as Bithermical multiorgan preservation, where abdominal organs are preserved in normothermia and thoracic ones in hypothermia. However, this methodology has not been scientifically proven. We have reproduced in a laboratory lung function assessment manoeuvres of pulmonary grafts from non heart beating donors. Then we have compared the correlation with the lung function assessment before cardiac arrest, applying the procedure on 40 pigs. Outcomes are promising.