आणविक और आनुवंशिक चिकित्सा

Identification and Description Case Report of a New HLA-A*33 Allele by Next Generation Sequencing Technology in a Brazilian Bone Marrow Donor

Abstract

Flavia Zattar Piazera1*, Marcelo Mion2, Guilherme Augusto Costa Damasio2, Cynthia Ellen Toyoshima Greenfield2, Rafael de Sá Vasconcelos3, Jorge Vaz Pinto Neto3 and Selma Aparecida Kuckelhaus1

New A*33 allele has the closest match with HLA-A*33:03:01:01, except for a mismatch at position 270 in Exon 2. Instead of the expected T, an A was detected at this position. This information was included in the full Nomenclature report and contributed to the immunogenetic study.