Xi-Hu Yang, Liu Liu, Jian-Hui Xu, Yong-Jie Hu, Ping Zhang, Jia-Xuan Qiu
Purpose: To explore the relationship between XIAP and CIAP1 co-expression and the prognosis in HNSCC.
Experimental design: 69 patients were recruited in our study, expression level of XIAP and CIAP1 were examined in all patients, and was correlated with clinical outcomes of the patients.
Results: The patients whose tumors co-express high level of XIAP and CIAP1 presented poorer overall and disease-free survival rates than those whose tumors co-express low level of XIAP and CIAP1 (overall survival P<0.001, disease-free survival P<0.001).
Conclusions: Our results validate that co-expression of XIAP and CIAP1 prompted a worse prognosis.
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