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The Role of Genetics in Adenocarcinoma Development and Progression


Jasinel Johan*

Adenocarcinoma, a malignancy originating in glandular cells, is influenced significantly by genetic factors in its development and progression. This article explores the intricate relationship between genetics and adenocarcinoma, highlighting familial syndromes, genetic mutations, and molecular mechanisms. Genetic predisposition and mutations in specific genes elevate the risk, while oncogenes, tumor suppressors, and epigenetic changes drive progression. Genomic profiling enables targeted therapies, but challenges persist. Genetic counseling plays a crucial role in risk management and prevention. With advancing research, personalized medicine offers hope for more effective adenocarcinoma treatments. Understanding genetics in adenocarcinoma promises improved detection, treatment, and prevention strategies.

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