Matthew Banerji
Chronic Lymphocytic Leukemia (CLL) is a common hematologic malignancy characterized by the accumulation of mature B lymphocytes in the blood, bone marrow, and lymphoid tissues. Historically, the backbone of CLL therapy has been fludarabine-based regimens for fit patients. However, the landscape of CLL treatment has transformed with the emergence of targeted agents, such as B-cell receptor signaling inhibitors and BCL-2 inhibitors. This article reviews the impact of targeted agents on the survival outcomes of CLL patients who are deemed fit for fludarabinebased therapy. It examines clinical trials, real-world evidence, and expert opinions to provide insights into the evolving treatment paradigms and the implications for clinical practice.
इस लेख का हिस्सा
English 
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Telugu 