Coralie Reimerink
The outbreak of Zika virus has posed significant global health challenges, necessitating the development of rapid and accurate diagnostic tools. This study presents the development of a point-of-care diagnostic test for Zika virus infection utilizing CRISPR-Cas12a technology. Leveraging the specific and robust targeting capability of CRISPR-Cas12a, we designed a diagnostic platform capable of detecting ZIKV with high sensitivity and specificity. The assay demonstrated a limit of detection comparable to existing laboratory-based methods but with the advantage of faster results and minimal equipment requirements. This CRISPR-Cas12a-based diagnostic test offers a promising solution for timely and effective ZIKV detection, especially in resource-limited settings.
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