El- Desouky TA*, El Sayed TI, Abd El Aziz AM, Reham M. Mostafa and Ashraf S.A. El-Sayed
The biosynthesis of silver nanoparticles (AgNPs) by plant extracts is a preferred method because it is an environmentally safe, fast and low cost method. Therefore, this study aimed to use aqueous extracts from (Sonchus oleraceus and Cichorium pumilum) to synthesize AgNPs, and their evaluation antifungal activity and inhibitory impact on the production of aflatoxin B1 (AFB1) produced by the new strain Aspergillus aflatoxiformans, and A. ochraceou that produce ochratoxin A (OTA). AgNPs synthesized by S. oleraceus give size ranged between 6 and 30 nm, While AgNPs synthesizedby C. pumilum sizes ranging from 3-36 nm. The inhibition zone with A. aflatoxiformans was 33.3±7.6, and 30.7±5.13mm at 400ppm from AgNPs synthesized by S. oleraceus and C. pumilum, respectively, while with A. ochraceus the inhibition zone increased to (35.0 ± 5.0 and 37.0 ± 4.3 mm). Finally, this study recorded for the first time, the impact of AgNPs on growth and ability of A. aflatoxiformans to produce AFB1. The inhibition percentage of AFB1 reached to 97%.
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