जर्नल ऑफ ऑन्कोलॉजी मेडिसिन एंड प्रैक्टिस

Oncology clinical care is continually evolving, driven by advancements in research, technology and a deepening understanding of the complex nature of cancer. This abstract outlines strategies and innovations aimed at enhancing the quality of oncology clinical practices, with a focus on improving patient outcomes, optimizing treatment protocols and fostering multidisciplinary collaboration. The first section delves into personalized medicine and its role in tailoring oncological treatments to individual patients. We explore the integration of genomics, biomarkers and molecular profiling to identify targeted therapies, minimizing adverse effects and maximizing treatment efficacy. Emphasis is placed on how these innovations contribute to a paradigm shift in oncology, moving towards precision medicine. Next, the abstract discusses the significance of data-driven approaches in oncology clinical quality. Harnessing the power of big data, artificial intelligence and machine learning enables healthcare providers to extract meaningful insights, predict treatment responses and identify patterns that inform evidence-based decision-making. Effective communication and collaboration among various healthcare professionals, including oncologists, surgeons, radiologists and nurses, are vital for comprehensive cancer care. Strategies for fostering interdisciplinary teamwork and improving communication channels are highlighted.

Background: In Taiwan, the incidence of Malignant Pleural Mesothelioma (MPM) has been increasing over the past three to four decades. This study aimed to analyze the outcomes and overall survival rates in patients undergoing cytoreductive lung-sparing decortication pleurectomy surgery and intraoperative adjuvant therapy (hyperthermic intrathoracic chemotherapy or photodynamic therapy) for malignant pleural mesothelioma at a single center in Taiwan.

Methods: This was a retrospective review of patients who underwent cytoreductive lung-sparing decortication pleurectomy surgery and intraoperative adjuvant therapy for malignant pleural mesothelioma from April 2013 to December 2021.

Results: A total of 17 patients with malignant pleural mesothelioma underwent surgery. There was one case of surgical mortality due to intraoperative uncontrolled bleeding. The subtypes according to histology were epithelioid mesothelioma (58.8%), pleomorphic subtype of epithelioid malignant mesothelioma (5.9%), biphasic mesothelioma (11.8%), and sarcomatoid mesothelioma (23.5%). The median survival was 14.0 months. However, for the epithelioid type, the median survival was 20.0 months.

Conclusion: To our knowledge, this is the first report from a single center in Taiwan devoted to lung-sparing decortication pleurectomy with intraoperative adjuvant therapy for malignant pleural mesothelioma. Although our hospital did the most operations for patients with malignant pleural mesothelioma in Taiwan, we were still far away from being a high-volume center in the world. The outcome is not satisfactory, but still slightly better than that of patients who received chemotherapy alone, especially those with the epithelial subtype disease. One of our patients survived for more than 6 years. We provide an option for the treatment of patients with malignant pleural mesothelioma in Taiwan.

Mentoring plays a pivotal role in the development and progression of professionals in the field of radiation oncology. As a complex and everevolving specialty, it demands not only expertise but also guidance, support and continuous learning. Mentoring relationships, characterized by the transfer of knowledge, skills, and wisdom, are crucial in shaping the careers of aspiring radiation oncologists, ensuring the delivery of high-quality patient care, and fostering the future of the field. The discussion further explores how mentorship facilitates the development of critical thinking skills, hands-on technical expertise, and adaptability to clinical challenges. The abstract underscores the role of mentoring in bridging the gap between theoretical knowledge and practical application, preparing mentees for the complexities of their roles. It emphasizes the perpetuation of expertise through effective mentorship, leading to sustained knowledge transfer and encouraging innovation in the field. The conclusion reinforces mentorship as the cornerstone of success in radiation oncology, shaping individual careers and influencing the advancement of the entire field. The abstract concludes by advocating for structured mentorship programs, diversity and continuous learning to strengthen the mentorship culture in radiation oncology. It envisions a future where mentorship remains integral to shaping the next generation of radiation oncologists and pushing the boundaries of knowledge and practice in patient care and innovation.