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मस्तिष्क संबंधी विकार

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आयतन 4, मुद्दा 2 (2016)

मामला का बिबरानी

A Pediatric Case of Solitary Myofibroma

Yukihiro Goto, Hiroyasu Sasajima, Yuichi Furuno, Takuya Kawabe, Kei Ohwada, Kazunori Tatsuzawa, and Naoya Hashimoto

A 5-year-old male was referred to our department for evaluation of a firm elastic mass at the back of his head. Clinical examination revealed no abnormalities but the local area was tender. Further clinical and radiological examinations yielded no pathological findings and no other lesions were detected. The lesion was located in the diploic layer of the left parietal bone. The inner layer of the skull intact but the outer layer showed osteolytic change. The lesion did not adhere to the dura mater. The tumor was completely removed with the surrounding bone. Histological examination revealed a mesenchymal tumor comprised of myoid spindle-shaped cells arranged in whorls between muscle cells and fibroblasts and a vascular component around the spindle cells. The final diagnosis was myofibroma. The patient recovered well after the operation and he was discharged from hospital 10 days after surgery. Clinical and radiological follow-up 6 and 12 months later showed neither recurrence of the primary lesion nor any indications of lesions at other sites. Myofibroma is a benign neoplasm composed of myoid cells with thin-walled blood vessels. This tumor, reported to have a wide range of clinical manifestations, is one of the cranial vault tumors. These tumors occur mainly in children although a few affected infants have been reported. Surgical intervention may contribute significantly to the diagnosis of solitary myofibroma and complete removal achieves good outcomes. Herein, we report a 5-year-old male with solitary myofibroma of the skull, presenting as a firm elastic mass in the left parietal bone.

संपादकीय

Good Smile, Healthy Brain?

Souvik Sen and Lauren Dennis Giamberardino

Periodontal disease is an infectious disease causes my microorganisms resulting in the corrosion of tissues around the tooth surface and soft tissue lining the mouth, loss of connective tissue attachment, breakdown of bone that holds the teeth, and tooth loss. The symptoms are bleeding gum (gingivitis), gingival pockets and bone loss (periodontal disease) leading to tooth mobility and eventually tooth loss. In the United States, periodontal disease is very prevalent and becomes more prevalent in aging populations. According to a recent survey in the United States, approximately half of adults have some level of periodontal disease and almost 10% of those have severe disease.

शोध आलेख

Effects on Upper-Limb Function with Dynamic and Static Orthosis Use for Radial Nerve Injury: A Randomized Trial

Cantero-Téllez Raquel, Gómez-Martínez Miguel and Labrador-Toribio Cristina

The management of radial nerve palsy associated with humerus’s shaft fractures has been discussed for several decades, instead, is the most common nerve complication after humeral shaft fracture. Indeed, radial nerve palsy recovery rate ranges from 70 to 90%, many reports related to the use of dynamic orthosis options are described in the literature. The purpose of this study is to determinate which orthosis or splint is the best option to improve patient’s upper limb function, measured with DASH (Disability arm shoulder and hand) questionnaire when surgical intervention is not indicated. Final sample size consisted of 18 participants (14 men and 4 women) with an average age of 46 who suffered from a radial nerve lesion in the dominant arm after humerus’s shaft fractures were included in the study. Participants were randomized into 2 equal groups (9 patients for the static orthosis or splint group and 9 for the dynamic orthosis/splint group). The variance analysis showed a main effect in time lapse (F (1, 58) = 71, P<0.001) indicating a significant improvement in function. Results were significantly better for the static orthosis/splint group than for the dynamic splint group. Treatment with static orthosis produces further improvement in function compared to the treatment with dynamic orthosis.

संपादक को पत्र

First Skin Biopsy Reports in Children with Autism Show Loss of C-Tactile Fibers

Louisa Silva and Mark Schalock

Autism is the most common developmental disability, affecting 1/45 children. Its cause remains unknown. Clinically, it is defined by the appearance of social/language delay, unusual, repetitive behavior, and abnormal sensory responses by the age of 3. Abnormal responses to touch are amongst the earliest and most universally prevalent of abnormal sensory symptoms. In 2013, when abnormal sensory responses were reclassified from co-morbid symptoms of two core diagnostic symptoms, the need for definitive evaluation of the sense of touch was recognized. Children with autism are distinguished both by lack of interest in affective and affiliative touch and by a generalized pattern of allodynia and hypoesthesia affecting multiple areas including the face, mouth, hands and feet.

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