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आयतन 6, मुद्दा 1 (2020)

अनुसंधान

Efficacy and Safety of a Natural Keratin (Kera-Diet®) Hydrolysate on Hair and Nails. Randomized, Placebo-and Benchmark-Controlled Clinical Trial on Healthy Females Part 2

Vincenzo Nobile

Telogen effluvium (TE) is one of the commonest occurrences in a trichology clinic, with patients claiming excessive hair shedding. TE is so frequent and worrying as to convey urgently the patient to the dermatologist and to extend the complaint even to social blogs on the web worldwide. In its acute (aTE) form, telogen effluvium clinical course duration does not exceed 6 months. The excessive hair shedding typical of aTE is triggered when a large number of hair in the growing phase of the hair cycle (anagen) prematurely and abruptly enter the resting phase (telogen). The duration of the interruption of the anagen hair growth is not noticed by the patient since the mitotically inactive nature of telogen. Hair shedding is noticed by patients only when hair re-enter the anagen phase and a new hair displace the telogen hair from the follicle. The interruption of mitosis, leading to aTE, may occur on account of chemotherapeutic drugs, acute febrile illness, postpartum hormonal changes, hypothyroidism, iron/zinc deficiency, seasonal variation, crash dieting, low protein intake, and malnutrition. aTE can occur in people of any age and ethnicity and is considered to be a quite common condition in either sex. Women are more likely to have lowered quality of life and restricted social contacts as compared to men as a result of hair loss even if the loss of hair becomes a matter of concern in all individuals irrespective of age and sex. Nail plate fragility is a common condition affecting up to 20% of the population, especially women over 50 years of age, characterized by roughness of the surface of the nail plate, tendency of the nail to peel and split, and fragility of the distal nail. According to causative factor, 2 forms of nail fragility can be distinguished: a primary "idiopathic or brittle nail syndrome" form (BNS) and NF secondary to different causes such as inflammatory nail disorders, infections, systemic diseases and general conditions, traumas and alteration of the nail hydration. Nails affected by BNS appear ragged, thin, and dull. The clinical features of BNS include horizontal splits within the nail plate (onychoschizia) and increased longitudinal ridging or splitting (onychorrhexis): the impairment of intercellular adhesive factors of the nail plate is expressed as onychoschizia; while the involvement of the nail matrix is expressed as onychorrhexis. The majority of subjects experiencing BNS indicate that these nail abnormalities are painful, impair daily activities, and may have a negative impact on occupational abilities. In BNS oral supplementation, trace elements and amino acids (especially cysteine) have been reported to be useful to ameliorate the nail plate condition. BNS is also associated with the presence of depressive disorders, indicating a possible impact on the quality of life of those who experience them, similarly to what occurs with hair loss perception.

संपादकीय

Note on Journal of Cosmetology & Trichology

Jeffrey C.H. Donovan

I am happy to disclose that Journal of Journal of Cosmetology & Trichology is an open access scientific journal and that gave me chance to bring forward the achievements of the journal in the year 2019. We published quite a lot of papers in the year 2019, in 2019 these discoveries were new. The ISSN of JCTT is 2471-9323 and publisher of JICTT is Hilaris publisher

समीक्षा

Natural and Organic Cosmetics: Definition and Concepts

Cleber Barros and Rosana Bevenuto Guilhen

The market of natural and organic cosmetics has been growing in last decades. The increase in interest in this type of product is a consequence of the concern that consumers have been presenting in relation to the environment and health. In addition to the appreciation the use of sustainable ingredients in cosmetic formulations, the consumers are also concerned about pollution caused by the use of plastics, which leads industries to reinvent themselves and rethink about the composition of packaging. The factor that most drives the purchase of natural and organic cosmetics are the fact that the consumer, in addition to contributing to the preservation of the environment, is also using a sustainable product. The growing demand for natural and organic cosmetics results in a concern of the brands with the organic issue, with the decreased use of animal derived ingredients and with the updating the parameters required for certification of a cosmetic as natural or organic. Due to the few studies available in this area, the importance of clarifying the definitions and concepts of natural and organic cosmetics is evident, in order to contribute with accurate information for the cosmetic sector.

शोध आलेख

Vacuum Therapy in Association with Plant Active Compounds, Prebiotics and Probiotics for Treatment of Androgenetic Alopecia, Female Pattern Hair Loss and Telogen Effluvium

Airton Toffanello, João Paulo Correia Gomes and Carla Aparecida Pedriali Moraes

The aim of this work was to develop and test an alternative hair loss treatment using vacuum therapy in association with cosmetic emulsions containing plant-based active compounds, prebiotics, probiotics and growth factors, inducing remission of androgenetic alopecia, female pattern hair loss and telogen effluvium alongside their associated symptoms.

संपादकीय नोट

Efficacy and Safety of L-Cystine Associated or not to a Natural Keratin (Kera-Diet®) Hydrolysate on Hair and Nails: Randomised, PlaceboControlled, Clinical Trial on Healthy Females

Vincenzo Nobile

The acute Telogen Effluvium (aTE) and the Brittle Nail Syndrome (BNS) are two medical conditions affecting both males and females. A dietary approach based on aminoacids and/or on protein hydrolysate could be a safe and effective approach in reducing hair loss during acute telogen effluvium and in improving brittle nails conditions. 

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