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Post Traumatic Epilepsy: A Review of Triggers and Potential Treatments after Brain Injury

Abstract

Emily McDonnell and Stephanie A Kolakowsky-Hayner

Posttraumatic epilepsy (PTE) is a significant and debilitating issue further complicating recovery after brain injury. This review is meant to be an overview of PTE following traumatic brain injury (TBI). Beginning with an introduction into the epidemiology of PTE following TBI, the paper goes on to explain the classifications of seizures and what defines posttraumatic epilepsy as well as the risks associated with the development of PTE after TBI. The biological basis of PTE is explained using both past and current research, assisting in understanding the past and current treatment options. This review concludes with a discussion of future research directions in order to improve upon the dearth of knowledge in this area and further build and establish well utilized treatment options.

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