..

जर्नल ऑफ़ क्लिनिकल केस रिपोर्ट्स

पांडुलिपि जमा करें arrow_forward arrow_forward ..

Oxidative Stress after Iron Supplementation in Crohn's Disease

Abstract

Marcia Morandi Varela Junqueira-Franco, Carolina Ferreira Nicoletti, Carla Barbosa Nonino, Hélio Vannucchi and Julio Sergio Marchini

Crohn’s disease is a chronic inflammatory intestinal disease associated with increased of pro-inflammatory cytokines, iron deficiency and anaemia. This case report demonstrates a strategy for intravenous iron supplementation in a patient with Crohn´s disease and severe anaemia. This study found an increased in iron and haemoglobin concentrations, malondialdehyde and superoxide dismutase levels and a reduction in glutathione peroxidase (GPx), vitamin A and E. In conclusion the use of intravenous iron probably leads to increase ROS production; this effect may be reduced by using polivitaminics, and enhanced the free radical scavenger.

अस्वीकृति: इस सारांश का अनुवाद कृत्रिम बुद्धिमत्ता उपकरणों का उपयोग करके किया गया है और इसे अभी तक समीक्षा या सत्यापित नहीं किया गया है।

इस लेख का हिस्सा

में अनुक्रमित

arrow_upward arrow_upward