स्वास्थ्य एवं चिकित्सा सूचना विज्ञान जर्नल

Interactome Analysis for Identification of Common Drug Targets in Salmonella Species

Abstract

Nikita Chordia, Priyesh Hardia and Priya Jain

A wide variety of human population is infected with different species of Salmonella causing salmonellosis. At present, the major hurdle in treating infection is the development of resistance to existing antibiotics. Therefore, there is a need to identify new drug targets so that new drugs can be designed that can cure the infection efficiently. Here, we have design an interactome for all species of Salmonella using its essential and non-homologous protein to humans. So that, all types of infections of Salmonella can be treated with single antibiotic. 1399 essential proteins of Salmonella have been analyzed using interactome studies. We found 09 proteins as putative drug targets that can be used to treat all species of Salmonella.