Huanhong Zeng, Xin Zhou, Haiting Xie, Yangyu Zhao and Wei Fu
Gastric cancer associated with pregnancy is quite rare, and it is often diagnosed late due to misinterpretation of clinic presentations as pregnancy-related digestive symptoms. Most pregnancy-associated gastric cancer is often at its advanced stage at the time of diagnosis. The difficulties in the early diagnosis of gastric cancer in pregnant women deter timely surgical treatment for the disease. We reviewed the existing literature using the key words “pregnancy” and “gastric cancer”. 65 cases, including 62 cases reported previously in China and 3 cases that we report here, were accumulated. The analysis of these and other 29 cases from Japan revealed that the pathology of such kind of tumor mostly were poorly differentiated diffuse carcinomas. Some further examinations should be conducted timely on the pregnant patients with persistent gastrointestinal symptoms for the differential diagnosis of hyperemesis gravidarum. As soon as gastric cancer was diagnosed, a therapeutic plan should be promptly made by obstetric and gastric cancer specialists.
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