Kota V Ramana
The volume 5 and 5th issue of Journal of Clinical Case Reports compiles 13 excellent manuscripts including 9 clinical case reports and a research article on various pathological conditions. An interesting research article by Vega-Hernandez et al, described the association between four polymorphisms on the Vitamin D Receptor (VDR) with respect to clinical manifestations of Psoriasis Vulgaris (PsV) in a Mexican patient population. Their results indicate polymorphisms of FokI, ApaI, BsmI and TaqI in the VDR gene are not associated with the risk of presenting PsV in the Mexican population. They found an association between FokI polymorphism of VDR gene and two major clinical variables, suggesting that the genotype [T/T]/ff may be a protective factor for nail involvement and age of onset in Mexican patients with PsV.
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