Ozlem Cakici*
Surgery is now an acceptable, and in many cases the only, treatment option for carefully selected infants and children with intractable severe epilepsy, including infantile spasms (ISS) (Engel, 1996; Mathern et al., 1999; Peacock et al., 1996; Sisodiya, 2000; Wyllie et al., 1996). The specimens obtained from such procedures have provided neuropathologists with novel brain tissues that may provide clues to the pathogenesis of ISS as well as epileptic syndromes.
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