Hector E. Hernandez, Zin Htway and Andrew Eichner
The complex relationships between chronic kidney disease (CKD), type 2 diabetes, and anemia poses a difficult clinical challenge. The interrelationships between these diseases typically affect hematological profiles in CKD patients. There is a paucity of literature regarding the effects of anemia on patients with CKD and type 2 diabetes in any single ethnic group. We investigated hematologic levels associated with anemia between patients with and without a type 2 diabetes diagnosis within a single ethnic population. A cohort of adult Hispanic, hemodialysis patients attending seven dialysis facilities in San Antonio, Texas was recruited for this retrospective study. Medical record data were collected to ascertain three hematological indicators of anemia: hemoglobin, serum ferritin, and transferrin saturation (TSAT) level. A statistically significant difference for hemoglobin and serum ferritin levels between patients with and without type 2 diabetes was not identified. However, TSAT levels showed a statistically significant difference between both groups. Type 2 diabetic patients exhibited a lower TSAT level of 21.24 ± 9.67%, compared to their non-diabetic counterparts at 23.64 ± 12.19%. Our findings underscore the need for diverse anemia clinical care in patients with a type 2 diabetes diagnosis, and incite the need for further research in this discipline.
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