पशु चिकित्सा विज्ञान एवं प्रौद्योगिकी

Antioxidant Trace Elements and Oxidative Stress Levels Associated with Pasteurellosis in Camel-Calves (Camelus dromedarius)

Abstract

Sherif Mohamed Shoieb, Hussam Mohamed Mohamed Ibrahim, Mohamed Sayed-Ahmed* and Sabry Ahmed El-khodery

The aim of the present study was to evaluate changes in the electrolyte and trace elements profiles, antioxidants and oxidative stress level associated with pneumonic pasteurllosis in camel-calves in Saudi Arabia. For this purpose, venous blood samples were obtained from 48 camel-calves with pneumonic pasteurellosis and 48 randomly selected clinically healthy camel-calves (control group). Serum trace elements including sodium, potassium, chloride, copper and zinc were assayed. Serum malondialdehyde and low-density lipoprotein levels as well as total antioxidant capacity; hydrogen peroxide concentration; and activity of reduced glutathione, catalase, and superoxide dismutase were measured. Moreover, copper/zinc ratio and oxidative stress index were calculated. In camel-calves with pneumonic pasteurellosis, there was a significant (P<0.05) decrease in the level of serum sodium, potassium, chloride, copper and zinc; total antioxidant capacity; and the activity of reduced glutathione, superoxide dismutase and catalase when compared with control group. Meanwhile, there was a significant (P<0.05) increase in copper/ zinc ratio; level of malondialdehyde and low density lipoprotein; concentration of hydrogen peroxide; and oxidative stress index in pneumonic camel-calves compared to control group. The results indicate that electrolyte profiles, trace element level and oxidants antioxidants balance are greatly disturbed in camel-calves with pasteurellosis.