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A Diffuse Pulmonary Presentation of Benign Metastasizing Leiomyomas Fawwaz R Shaw

Abstract

Fawwaz R Shaw

Benign metastasizing leiomyomas of the lung remain an infrequently encountered pulmonary pathology with poorly understood pathogenesis and unclear treatment algorithm. They may manifest a spectrum of clinical symptoms and have multiple proposed etiologies. Critical to this diagnosis is adequate tissue biopsy, which additionally may facilitate treatment based on hormonal receptor status.

Complete surgical resection of solitary pulmonary lesions is advocated with targeted endocrine therapy as a proposed means of treating disseminated disease. Long term follow up of these patients is critical to our understanding of the risk of recurrence, malignant transformation and natural history of this disease.